Zepdon

ABOUT ZEPDON?  

ZEPDON  contains the active substance raltegravir and as an antiviral drug affects against human immunodeficiency viruses (HIV).

HOW ZEPDON WORKS?

·         The virus produces an enzyme called HIV integrase, which helps in virus multification in  the organism.

·         ZEPDON  prevents the effect of the  enzyme and  in the  combination with others medicines, ZEPDON  affects on a reduction of HIV  virus.

·         It’s effect  on an increase of white blood cells,  are important  in preserving

·         function of the immune system in the fight against the infections.

THE INDICATION FOR USE?

ZEPDON  are used in the treatment of adult and pediatric patients who are infected with HIV, with a body weight of at least 40 kg

WHAT ARE WARNINGS AND PRECAUTIONS THAT YOU SHOULD BE INFORMED OF?

• Psychic Problems
  
              Tell your doctor if you have depression or psychiatric illness. 
  
  
• Bone Diseases
  
              Some patients with combined  antiretroviral therapy, an osteonecrosis can be developed. 
  
  
• Liver Disease

                    Inform you  doctor if you have had a previous a liver disorder including hepatitis B or  C.

• Transferring HIV To Other People
  
             HIV infection is transmitted through contact with an infected person through blood or sexual contact with  a person infected with HIV.            HIV can be transmitted even while you are taking this medicine.
  
  
• Infections
  
           Inform you  doctor if you have immediately if you notice any of the symptoms of infection, such as fever and/or a general feeling of                 weakness.
  
  
• Muscular Disorders
  
          Immediately contact your doctor if you experience unexplained muscle pain, sensitivity or weakness during therapy
  
  
• Skin Disorders
  
          Talk to your doctor immediately if you get a rash.

ZEPDON  AND THE USE OF OTHER MEDICINES?

 You should inform  your doctor if you have recently taken or will Take some of  the following medicines:

• Antacid (drugs that suppress or neutralize acid in the stomach
• Atazanavir
• Rifampicin
• Tipranavir/ Ritonavir 
  
  

The USE OF  ZEPDON IN PREGNANCY AND BREASTFEEDING IS NOT RECOMMENDED

Driving and machine handling: 
Do not drive or use machines if you feel dizzy after taking this medicine

HOW IS ZEPDON  PRESCRIBED?

Adults, children, and adolescents :

The recommended dose is 400 mg , once a day, orally, regardless of the intake of food or drink.    

Swallow the whole tablet.

WHAT YOU SHOULD KNOW ABOUT SIDE EFFECTS?

• Immediately contact your doctor if you notice any of the following conditions:
  
  

  • Herpes infections, including herpes zoster
  • Anemia,
  • Infection or inflammation
  • Mental disorder
  • Intention or attempted suicide
  • Stomach inflammation
  • Liver insufficiency
  • Allergic rash
  • Kidneys disorder
  • Reduction of appetite
  • Sleeping disorders
  • Vertigo
  • Stomach pain; diarrhea; gases in the stomach or intestines; nausea; vomiting
  • Tiredness, unusual fatigue or malathion; fever
    
    
  • Inflammation of the upper respiratory tract,
  • lymph nodes abscess, swollen glands on the neck, under the armpits
    
    
  • Diabetes; increase in cholesterol
    
    
  • Significant weight loss
    
    
  • Anxiety; depression; mood swings;
  • Pain in the hands of the pressure of the nerve;
    
    
  • A headache  with a feeling of constant pressure, tremor
    
    
  • Visual Disturbance
  • Irregular heartbeat and high blood pressure
  • Prolonged constipation
    
    
  • Dry mouth; gooseberry
  • Pancreatits;
  • Bleeding from the anus;
  • Unusual loss and hair thinning; redness of the skin;
  • Unusual change of  fat deposits distribution, which includes loss of fat on the legs, arms and face, as well as the increase in fat
  • on the Stomach;
  • Joint, bone, back  or muscle pain
    
    
  • Stones in the kidneys;
  • Erectile dysfunction; breast increase in men; symptoms of menopause
  • Reduced number of white blood cells and blood platelets
    
    
  • A decreased renal function