WHAT IS XBIRA?
- XBIRA is an anti-tumor drug, which belongs to a group of drugs called aromatase inhibitors.
- The drugs of this group act on a substance called aromatase, and it is needed in the production of female hormone estrogens, especially in postmenopausal women.
- Reducing estrogen levels in the body is a way the treatment of an estrogen- depending breast cancer XBIRAis not intended for use in children.
THE INDICATION FOR USE:
- Hormone-dependent early breast cancer in postmenopausal women
- Hormone-dependent advanced breast cancer in postmenopausal women, when treatments with other hormonal drugs failed.
WHAT DO YOU NEED TO KNOW BEFORE STARTING A THERAPY?
Do not take XBIRA if you are:
- Allergic or have had an allergic reaction to an exemestane
- Still in a reproductive period
- Are pregnant or if you are breastfeeding.
WARNINGS AND PRECAUTIONS:
Inform your doctor if you are taking:
• Rifampicin (antibiotic)
• Carbamazepine or phenytoin
RECOMMENDATIONS FOR PREGNANCY, BREASTFEEDING, AND DRIVING:
You should not take XBIRA if you are pregnant or breastfeeding.
If you feel sleepy or weak during therapy, do not operate vehicles or machines.
HOW IS XBIRA USED?
- Adults and elderly patients:
- A recommended dose is one tablet or 25 mg daily, taken orally after a meal, at about the same time every day.
· - If you take more XBIRAthan you need contact your doctor immediately or contact your nearest hospital. Take a tablet box with you.
· - If you have forgotten to take a therapy do not take a double dose to make up for a forgotten tablet.
WHAT ARE KNOWN SIDE EFFECTS:
- Sleeping disorder
- A headache
- Waves of heat
- Increased sweating
- Muscle and joint pain (including osteoarthritis, back pain, arthritis and stiffness joints)
- Reduction in the number of white blood cells (leukopenia)
- Abdominal pain
- Elevated levels of liver enzymes
- Elevated levels of bilirubin in the blood
- Elevated levels of alkaline phosphatase enzymes in the blood
- The pain
- Loss of appetite
- A sensation of needle-sting and pain affecting the whole hand except a fist o finger- Carpal tunnel syndrome
- Pain in the stomach, vomiting, constipation, digestive disorders, diarrhea
- Hair loss
- Skin rash, rash, and itching
- Reduction of bone strength which can reduce their strength (osteoporosis),
- Swelling of the hands and feet
- A decrease in the number of platelets (thrombocytopenia)
- General weakness.
- The emergence of small bubbles in the skin affected by a rash