ABOUT PROFICENT injection?
- PROFICENT injection belongs to a group of medicines called gonadotropins (sex hormones).
- In women, it controls the release of ovarium cells and controls the production of the male hormone – testosterone, in men.
- PROFICENT injection contains the active substance - human chorionic gonadotropin (hCG) that plays a key role in fertility and reproduction.
WHAT ARE INDICATIONS FOR USE?
- For the induction of ovulation in female infertility
- As a co-therapy with other medicines in assisted reproduction
- PROFICENT injection is used in men for treatment when there is a small amount sperm.
- PROFICENT injection is also used in men before starting stimulant therapy
- when the reproductive organs do not work properly due to lack of it sex hormones.
- PROFICENT injection is used in children to treat delayed puberty and in children,
- in which the testicles did not descend or did not fully descend into the scrotum sac.
IN WHICH CONDITION DO NOT START WITH PROFICENT THERAPY?
- In sex, hormones depending tumors,
- In excessive ovarian stimulation
- In cryptorchidism of organic
ABOUT WHAT SHOULD YOU INFORM DOCTOR BEFORE USING PROFICENT?
- Talk to your doctor if you have kidney insufficiency, migraine, epilepsy, a problem with circulation, asthma or heart disorder.
- The use of PROFICENT is associated with an increased risk of excessive ovarian stimulation (hyperstimulation).
- If symptoms of excessive ovarian stimulation occur, treatment should be discontinued.
- Hospitalization is necessary in case of severe hyperstimulation (grade III), in which large ovarian cysts (ovarian size over 10 cm), ncreased hemoglobin, and increased platelet aggregation with an increase he risk of thromboembolism.
HOW IS PROFICENT APPLIED?
- Ovulation stimulation: a single intramuscular injection at a dose of 5000 IU up to 10000 IU HCG
- to support the function of the luteum: three intramuscular injections every third day
- Cryptorchidism in boys under the age of 2 years and over 6 years: one intramuscular injection per week in a dose of 500 IU up to 2000 IU HCG for a period of 5 weeks.
- In boys from 3 to 6 years of age, PROFICIENT is administered intramuscularly one dose per week for three
- Delayed puberty: 1500 IU HCG 2 to 3 times a week during the next 3 months.
- Hypogonadotropic hypogonadism: 1500 to 6000 IU HCG intramuscularly once a week in combination with human menopausal gonadotropin, HMG).
WHAT ARE SIDE EFFECTS:
- Following the combined treatment of with clomifene, may occur the overstimulation the ovaries, followed by large ovarian cysts, accumulated fluid in the peritoneum with possible thromboembolic complications.
- During treatment with PROFICENT, side effects such as transient may occur enlargement of the mammary glands, prostate and penis enlargement that can provoke spontaneous erections.