Fertigyn

• FERTIGYN contains the active substance chorionic gonadotropin belonging to a group of medicines called gonadotropins (full hormones). Controls the release of an ovum from the ovaries in women and controls the production of testosterone in men.

• Induction of ovulation
• In assisted reproduction

• Hypogonadotropic
• Delayed puberty
• Cryptorchism
• untreated testicles

• Hormone-dependent tumor of the breast, ovary, uterus, testicle, prostate, hypophysis or hypothalamus
• If you are a woman and have a disorder of full organs that are incompatible with pregnancy
• If you are a woman and you have a fibroid of the uterus that is incompatible with pregnancy
• Aabnormal or unexpected vaginal
• Ovarian cysts on the ovaries or enlargement of the ovary

• The probability of developing ovarian hyperstimulation syndrome (OHSS)
• Therapy with gonadotropic hormones may cause hyperstimulation syndrome ovarian (OHSS).
• This is a difficult medical condition in which the ovaries are overstimulated and the development of follicles is bigger than normal. In rare cases, severe OHSS can endanger life.
• Therefore, careful supervision OHSS leads to sudden accumulation of fluid in the abdomen and chest area and can cause creating blood clots.

• Severe abdominal islet and pain in the abdominal area
• Nausea
• Vomiting
• The sudden increase of the body mass due to fluid accumulation
• Diarrhea
• Reduced urine output
• Difficulty breathing

• In women, one injection is usually given to induce ovulation, and at most three injections for support the luteal phase that follows.
• Men are given injections several times a week for weeks or months depending on the problem. The treatment with FERTIGYN should last at least three months to achieve the expected improvement.

• Immune system disorders
• Rash or fever
• Local reactions at the site of application (bruise, pain, redness, islet or itching) may occur.

• Vascular disorders
• Respiratory disorders
• Gastrointestinal disorders such as vomiting and diarrhea
• Abdominal pain
• Ascites (accumulation of fluid in the abdominal cavity), as a complication
• Disorders of the reproductive system and breast
• Unwanted hyperstimulation of the ovary, mild or severe hyperstimulation ovary syndrome.
• Painful breasts, mild ovarian enlargement, cysts on the ovaries
• Big cysts on ovary prone to rupture (severe ovarian hyperstimulation syndrome).

• Disturbances of metabolism and nutrition After administration of high doses, water and sodium retention has been recorded, this is considered as a consequence of elevated production of androgens (male full hormones).
• Disorders of the reproductive system and breast
• HCG therapy can cause gynecomastia (breast augmentation in men).

WHAT IS FERTIGYN

FERTIGYN contains the active substance chorionic gonadotropin belonging to a group of medicines called gonadotropins (full hormones). Controls the release of an ovum from the ovaries in women and controls the production of testosterone in men.

FERTIGYN is used:

   In women:

      - Induction of ovulation

      - In assisted reproduction

   In men:

      - Hypogonadotropic

      - Delayed puberty

      - Cryptorchism

      - untreated testicles

BEFORE TAKING FERTIGYN YOU SHOULD NOT TAKE IT IF YOU HAVE:

· Hormone-dependent tumor of the breast, ovary, uterus, testicle, prostate, hypophysis or hypothalamus

·  If you are a woman and have a disorder of full organs that are incompatible with pregnancy

·  If you are a woman and you have a fibroid of the uterus  that is incompatible with pregnancy

·  Aabnormal or unexpected vaginal

·  Ovarian cysts on the ovaries or enlargement of the ovary

For women:

   - The probability of developing ovarian hyperstimulation syndrome (OHSS)

   - Therapy with gonadotropic hormones may cause hyperstimulation syndrome ovarian (OHSS).

   - This is a difficult medical condition in which the ovaries are overstimulated and the development of follicles is bigger than normal. In rare cases, severe OHSS can endanger life.

   - Therefore, careful supervision OHSS leads to sudden accumulation of fluid in the abdomen and chest area and can cause creating blood clots.

Immediately contact your doctor if you have:

    · Severe abdominal islet and pain in the abdominal area

    · Nausea

    · Vomiting

    · The sudden increase of the body mass due to fluid accumulation

    · Diarrhea

    ·  Reduced urine output

    ·  Difficulty breathing

 THE  FERTIGYN APPLICATION?

     ·  In women, one injection is usually given to induce ovulation, and at most three injections for support the luteal phase that follows.

     ·  Men are given injections several times a week for weeks or months depending on the problem. The treatment with FERTIGYN should last

at least three months to achieve the expected improvement.

WHAT ARE KNOWN SIDE EFFECTS?

General:

·   Immune system disorders

·   Rash or fever

·   Local reactions at the site of application (bruise, pain, redness, islet or itching) may occur.

In women:

·   Vascular disorders

·   Respiratory disorders

·   Gastrointestinal disorders such as vomiting and diarrhea

·   Abdominal pain

·   Ascites (accumulation of fluid in the abdominal cavity), as a complication

·   Disorders of the reproductive system and breast

·   Unwanted hyperstimulation of the ovary, mild or severe hyperstimulation ovary syndrome.

·   Painful breasts, mild ovarian enlargement, cysts on the ovaries

·   Big cysts on ovary prone to rupture (severe ovarian hyperstimulation syndrome).

In men:

· Disturbances of metabolism and nutrition After administration of high doses, water and sodium retention has been recorded, this is considered as a consequence of elevated production of androgens (male full hormones).

· Disorders of the reproductive system and breast

HCG therapy can cause gynecomastia (breast augmentation in men).