- CAPEGARD belongs to a group of medicines called "cytostatic medicines" that prevent the growth of tumor cells. CAPEGARD contains an active substance capecitabine.
- CAPEGARD is used to treat cancer of the colon, rectum, stomach or breast.
- Furthermore, CAPEGARD is used to prevent the occurrence of a new colon tumor in patients whose tumors have been removed surgically.
- CAPEGARD is indicated for use in aduts, only.
What you should know before taking CAPEGARD?
Â· Do not take the medicine if you:
- Are allergic to capecitabine
- Have had severe reactions to anticancer drug fluorouracil
- Are pregnant or breastfeeding,
- Have a very low number of white blood cells or platelets in your blood (leucopenia, neutropenia or thrombocytopenia),
- Have severe liver or kidney disease,
- Are treated or have been treated with brivudine, sorivudine or for the last 4 weeks
WHAT SHOULD YOU TELL YOUR DOCTOR BEFORE THERAPY?
WARNINGS AND PRECAUTIONS:
Ask your doctor for an advice before taking CAPEGARD if you have:
- Liver or kidney disease
- Heart problems
- A brain disease, when a tumor spreads to the brain
- A calcium balance disorder
- Severe nausea and vomiting
- A mineral imbalance in your blood
- If you have severe skin reactions.
THE CAPEGARD INTERACTION WITH OTHER MEDICINES?
Before starting treatment, tell your if you are taking any of the following medicines:
- Coumarin, warfarin
- Sorivudine, brivudine
- Interferon alpha
- Drugs to treat cancer (folinic acid, oxaliplatin,bevacizumab, cisplatin, irinotecan),
Pregnancy and breastfeeding
- You should not use CAPEGARD if you are pregnant , think that you may be pregnant or during breastfeeding.
How to take CAPEGARD?
- The dose of CAPEGARD is dependent on the size of your body surface.
- Your doctor may prescribe a combination of 150 mg and 500 mg tablets for a single dose.
- Swallow the whole tablets in the morning and in the evening , within 30 minutes of after meals.
- CAPEGARD tablets are usually taken for 14 days with the following
- 7-day break (when no tablets are taken). This 21-day period represents one treatment cycle.
WHAT IF YOU HAVE TAKEN MORE MEDICINE THAN PRESCRIBED?
If you have taken much more CAPEGARD than you should you can experience following symptoms:
Â° Feeling sick or nausea,
Â° Dnflammation or sores in the intestine or mouth,
Â° Decrease of a bone marrow function
Â° Do not take the missed dose again.
Â° Do not double the next dose to replace the missed dose.
WHAT ARE KNOWN SIDE EFFECTS?
- Inflammation of the oral mucosa:
- Hand and foot skin reactions:
- chest pain:
- the decrease in the number of white or red blood cells (found in tests)
- dehydration, weight loss,
- insomnia depression,
- headache, drowsiness, dizziness, tingling skin sensations
- eye irritation, conjunctivitis,
- shortness of breath, cough,
- pneumonia or bronchitis
- constipation, upper abdominal pain,
- digestive problems,
- skin rash, hair and skin loss, itching, change in skin color, skin inflammation
- pain in joints, limbs, chest or back
- fever, swelling of the limbs,
- urinary tract infections, skin, nose and throat infections,
- Confusion, panic attacks, decreased libido
- Impaired memory,
- Foggy or double vision
- Irregular heartbeat and heart attack
- Blood clots in deep veins, irregular blood pressure,
- Purple spots on the skin
- Pulmonary embolism, lung collapse, blood coughing,
- Obstruction of the intestine, accumulation of fluid in the abdominal cavity,
- Inflammation of the bowel, stomach or esophagus, lower abdominal pain,
- Returning stomach contents to the esophagus,
- Blood in the stool,
- Skin ulcers and blisters,
- Stenosis of the lacrimal canals
- Liver failure.