Lopimune

ABOUT  LOPIMUNE?

 - LOPIMUNE is an antiretroviral drug.

 - LOPIMUNE is intended for the treatment of adults and children older than 2 years who are infected with HIV so that it works by slowing the spread of infection in an organism.

WHAT DO YOU NEED TO KNOW BEFORE YOU TAKE LOPIMUNE?

 Do not take medicine if you:

  - Have severe liver damage

  - Are taking one of the following medicines at the same time:

  - Astemizole or terfenadine

  - Oral midazolam, triazolam

  - Pimozide

  - Cisapride

  - Ergotamine, dihydroergotamine,

  - Amiodarone

  - Lovastatin, simvastatin (medicines for lowering cholesterol levels);

  - Alfuzosin - used in men with symptoms of enlargement of the prostate

  - Colchicine    

  - Vardenafil

  - Sildenafil

IMPORTANT INFORMATION:

   - LOPIMUNE can not cure HIV infection or AIDS.

  - LOPIMUNE does not reduce the risk of HIV transmission to other people.

    Appropriate precautions should be applied in order to prevent the transmission of infection to other people.

YOU SHOULD CONTACT YOUR DOCTOR OR HAVE:

  - Hemophilia type A or B,

  - Diabetes,

  - Liver disorder, including chronic hepatitis B or C

THE USE WITH OTHER DRUGS?

Tell your doctor if you are taking any of the following medicines,

  - Antibiotics (, clarithromycin);

  - Anti-cancer drugs (vincristine, vinblastine);

  - Anticoagulants-  warfarin,

  - Antidepressants

  - Anti-fungal drugs

  - Drugs in gout therapy

  - Drugs for the treatment of chronic hepatitis C -

  - Drugs for erectile dysfunction

  - medicines for heart rhythm disorders

  - Medicines for lowering cholesterol in the blood

  - Drugs in the treatment of pulmonary arterial hypertension

  - Drugs for smoking cessation (eg bupropion);

  - Morphine-like drugs

  - Sedatives medicines

  - Steroids

The Application of  LOPIMUNE medication during pregnancy and lactation?

  - The use of LOPIMUNE during pregnancy and lactation is not recommended.

  - Women infected with HIV are not recommended for breastfeeding. The possible influence of LOPIMUNE on the ability to drive vehicles and machines was not specifically investigated

HOW IS LOPIMUNE PRESCRIBED?

 The adults:

    - The usual adult dose is 800mg/200 mg  once a day, taken in two intervals during a day( morning and evening)

 The children:

   - LOPIMUNE is present in the strength of 100 mg / 25 mg

   - The appropriate dose (number of tablets) for children will be determined by the doctor based on the height and weight of the child.

WHAT ARE POSSIBLE SIDE EFFECTS?

  - Nausea;

  - Vomiting,  abdominal pain, lower and upper abdominal pain, gases, digestive disorders,

  - Inflammation of the stomach, intestines, and colon;

  - High blood pressure

  - Diabetes, weight loss;

  - Rash, eczema, swelling of the skin;

  - Dizziness, anxiety, sleep disorders;

  - Fatigue

  - Hemorrhoids;

  - Inflammation of the liver,

  - Changes in the shape of the body or shape of the

  - Infection of the lower respiratory tract

  - Enlargement of the lymph nodes;

  - Impotence, painful or prolonged menstrual bleeding or lack of menstruation;

  - Muscle disorders,

  - Damage to the nerves of the peripheral nervous system;

  - Night sweats, itching, rash, including skin dandruff, skin infections

  - Heart disorder

  - Inflammation of blood vessels and capillaries

  - Uncontrollable trembling of the body

  - Constipation

  - Dry mouth

  - Presence of red blood cells in the urine

  - Fatty deposits in the liver, enlarged liver

  - Loss of testicular function

  - Reduced sexual drive,

  - Kidney inflammation

  - wounds and ulcers in the mouth, inflammation of the stomach and intestines